Psychedelic Therapy in Colorado
Colorado passed the Natural Medicine Health Act (Proposition 122) in 2022, becoming the second state with regulated psilocybin access. It decriminalized personal use of several natural psychedelics for adults 21 and older and created licensed Healing Centers, the first of which opened in 2025. Ketamine and esketamine also remain medical options.
Your paths to care in Colorado.
Regulated psilocybin services at licensed Healing Centers for adults 21+, plus medical ketamine and esketamine.
Adults 21+ may use, grow, and share certain natural medicines (psilocybin now; DMT, ibogaine, mescaline under review). Sales stay within the licensed system.
Healing Center services include preparation, a monitored session, and integration with a licensed facilitator. Localities can regulate, but not ban, centers.
Compare the routes, side by side.
We help you choose clear-eyed.
Our concierge compares legal routes, explains the rules in plain language, and helps you choose a path that matches your needs, values, and safety profile.
Psychedelic care in Colorado.
Colorado voters approved the Natural Medicine Health Act, Proposition 122, in November 2022, the most comprehensive statewide psychedelics measure to reach a ballot. It did two things at once: it decriminalized personal use, growth, and sharing of certain natural medicines for adults 21 and older, and it directed the state to build a regulated system of licensed Healing Centers and facilitators. Denver had already become the first US city to decriminalize psilocybin, in 2019, giving the state an early head start.
The program is overseen by the Colorado Department of Revenue's Natural Medicine Division and the Department of Regulatory Agencies, with a Natural Medicine Advisory Board guiding the rules. It began with psilocybin and psilocin, with DMT, ibogaine, and mescaline (excluding peyote) under review for possible addition in 2026. License applications opened in late 2024, and the first Healing Centers opened to clients in 2025.
Colorado deliberately learned from Oregon. It allows two facilitator licensing tracks rather than one, offers a lower-cost micro-healing center license for smaller practices, and, importantly, lets localities regulate but not outright ban Healing Centers, which avoids the wide access gaps Oregon has seen from county opt-outs. By early 2026 the state had licensed dozens of Healing Centers, with more applications pending, and early sessions in places like Boulder, Denver, and Aspen have shown both strong demand and the same affordability questions seen in Oregon.
As with any new system, the work is matching well and verifying licensing. Our concierge helps you confirm a center's and facilitator's status, compare Colorado with Oregon if you are weighing both, and plan preparation and integration.
What to budget for.
Psilocybin services at Colorado Healing Centers are paid out of pocket and are not insurance-covered, because psilocybin remains federally illegal. Early Colorado pricing has tracked Oregon's: published sessions in the Boulder area have ranged from roughly fifteen hundred to thirty-four hundred dollars, depending on dose, length, and whether the session is one-on-one or group. Each center sets its own pricing.
Because Colorado lets localities regulate but not ban centers, you may have more options closer to home than in Oregon, which can reduce travel costs. Still, plan for travel and lodging if needed.
Medical ketamine and esketamine follow separate pricing: esketamine (Spravato) is often insurance-covered for treatment-resistant depression, while IV or IM ketamine for mental health is usually off-label and out of pocket. Ask about HSA or FSA eligibility where applicable. Our concierge fees are separate from any provider's charges; see our pricing page.
Before any session, cover this.
- Share all medications, especially SSRIs and SNRIs, MAOIs, stimulants, and blood-pressure drugs.
- Review cardiac history, seizure risk, bipolar spectrum, psychosis risk, pregnancy, and sleep apnea.
- Confirm monitoring, chaperone policies, and emergency planning with any provider.
- If considering at-home or compounded ketamine, discuss supervision and current FDA alerts with your prescriber.
Learn more about our Safety and Harm Reduction principles.
What we do, and what we don’t.
What we do
- Education, safety screening guidance, and integration support
- Compare legal options and verify licensed programs
- Share the vetting questions we ask any facilitator
What we do not do
- Sell, supply, or store controlled substances
- Instruct on obtaining substances or connect to distributors
- Provide medical or legal advice
A closer look at Colorado.
Two things at once
Proposition 122 both decriminalized personal use of certain natural medicines and created a licensed Healing Center system. That dual design is broader than Oregon's services-only model.
Built on Oregon's lessons
Colorado launched two years after Oregon and adjusted: two facilitator tracks, a lower-cost micro-center license, and rules that let localities regulate but not ban centers, reducing access gaps.
More than psilocybin, eventually
The program started with psilocybin and psilocin. DMT, ibogaine, and mescaline (excluding peyote) are under review for possible inclusion in 2026.
Early centers, real demand
By early 2026 dozens of Healing Centers were licensed, with locations open in Boulder, Denver, Aspen, and beyond. Demand is strong, and affordability is the open question.
Care today: what people actually do
Colorado seekers can access psilocybin at a licensed Healing Center, use medical ketamine, or, since personal use is decriminalized, pursue private experiences that lack the structure and safety of a supported setting. We focus on supported, well-prepared, well-matched experiences.
Why this matters
A legal framework lowers some risk, but quality and fit still vary widely between centers and facilitators. Our concierge exists to help you choose with confidence and prepare and integrate properly.
Questions, answered plainly.
Is psilocybin legal in Colorado?+
Yes. Personal use, growth, and sharing of certain natural medicines is decriminalized for adults 21 and older, and supervised psilocybin services are available at licensed Healing Centers. Commercial sale outside the licensed system is not allowed.
What is a Healing Center?+
A Healing Center is a state-licensed location where adults 21+ can receive psilocybin services with a licensed facilitator, including preparation, a monitored session, and integration. A lower-cost micro-healing center license also exists for smaller practices.
Can I just use psilocybin at home?+
Personal use is decriminalized for adults 21+, but that is not the same as a safe, screened, supported setting. We focus on supported, well-prepared experiences, whether at a Healing Center or another appropriate route.
How much does it cost?+
Early Colorado Healing Center sessions have ranged from about fifteen hundred to thirty-four hundred dollars, depending on dose, length, and format. It is paid out of pocket and not insurance-covered. Each center sets its own pricing.
How is Colorado different from Oregon?+
Colorado both decriminalized personal use and created Healing Centers, uses two facilitator tracks, offers a lower-cost micro-center license, and lets localities regulate but not ban centers, which reduces the access gaps Oregon has seen.
Which substances are included?+
The program began with psilocybin and psilocin. DMT, ibogaine, and mescaline (excluding peyote) are under review for possible inclusion in 2026.
What should I ask a Healing Center or facilitator?+
Confirm their Colorado license, ask about experience and approach, who is present during the session, emergency planning, and what preparation and integration are included. These are the questions we ask before we match you.
Are there medical or medication contraindications?+
Share all medications, especially SSRIs and SNRIs, MAOIs, stimulants, and blood-pressure drugs, and review cardiac history, seizure risk, bipolar spectrum, psychosis risk, pregnancy, and sleep apnea with a qualified provider. This is general information, not medical advice.
Need help choosing? Let’s talk.
Our concierge can walk you through the legal options in your area, with no pressure and no sales pitch.