Psychedelic Therapy in Oregon
Psychedelic Therapy in Oregon
Last reviewed: September 22, 2025
Summary: Oregon offers licensed psilocybin services statewide at regulated service centers with licensed facilitators. Legal options also include medical ketamine and esketamine. Underground or ceremonial options exist and carry legal risk. We provide education, safety guidance, and integration support—we do not broker illegal activity.
Oregon legalized licensed psilocybin services statewide under Measure 109 (ORS 475A). Adults 21+ may participate at licensed service centers with a licensed facilitator; consumption occurs on-site after a required preparation session. No prescription or residency is required. Local jurisdictions may restrict operations. Ketamine and esketamine remain medical options.
How access works (OHA) · Oregon Psilocybin Services (OPS) · SPRAVATO REMS · Colorado Natural Medicine
How people access care
- Legal in Oregon: licensed psilocybin services at service centers (prep → administration on-site → integration) with a licensed facilitator; plus ketamine in medical settings and esketamine in REMS-certified programs.
- Legal in other states: regulated Natural Medicine options in Colorado. See our guides: Colorado.
- Underground or ceremonial options exist and carry legal risk. We do not broker illegal activity. Our concierge supports education, safety, and integration.
Not sure which path fits you?
Our concierge team helps you compare legal routes, understand rules in plain language, and choose a path that matches your needs, values, and safety profile.
Your access options
| Pathway | What it looks like | Key notes |
|---|---|---|
| Psilocybin services (in Oregon) | Preparation session → on-site administration at a licensed service center with a licensed facilitator → integration. | 21+ with ID; no prescription or residency required; consumption on-site only. Verify licensing. OHA: How access works |
| Ketamine or Esketamine (in Oregon) | Medical screening, supervised sessions, integration support recommended. | Esketamine (Spravato) is FDA-approved for TRD in REMS-certified sites; most mental-health ketamine uses are off-label. Official REMS |
| Natural Medicine services (Colorado) | Licensed Healing Centers and facilitators under state rules. | Program info · our Colorado guide |
| MDMA-assisted therapy | Not FDA-approved as of September 2025; access primarily via clinical trials. | FDA CRL publicly released |
| Underground or ceremonial | Community or private settings; safety practices vary. | We do not sell or supply substances, instruct on obtaining them, or broker illegal activity. Our concierge provides education, vetting criteria, and integration support. |
The psychedelic landscape in Oregon
What Oregon actually legalized
Under Measure 109 (now ORS 475A), Oregon created a statewide system for licensed psilocybin services. Adults 21+ can participate at a licensed service center with a licensed facilitator. You complete a required preparation session, the administration happens on-site at the center, and integration support follows. A medical diagnosis or prescription is not required.
What didn’t change
- Psilocybin is not a prescription drug in Oregon; this is a regulated wellness service, not medical treatment.
- At-home dosing, unlicensed sales, and public possession are not authorized by this program.
- Local cities/counties can restrict or opt out of licensed businesses—verify location availability before you book.
How people use the program
Most clients choose a service center based on facilitator fit, setting, and session format (individual or group). Some travel in-state for the right center; others coordinate with their healthcare providers for medical/medication review and then book preparation and integration support with us for continuity.
Other legal options in Oregon
Alongside psilocybin services, people access ketamine (typically off-label for mental health) and esketamine (SPRAVATO) in REMS-certified clinics with on-site monitoring. These are medical services and may have different eligibility, costs, and insurance considerations than psilocybin services.
References: OHA: How access works · Oregon Psilocybin Services (OPS) · SPRAVATO REMS
Costs and logistics
Ketamine and esketamine, total cost depends on assessment, number of sessions, supervision, and integration. Esketamine occurs only in REMS-certified sites. Coverage varies by plan.
Psilocybin services in Oregon or Colorado, licensed centers set session pricing plus preparation and integration. Add travel and lodging. Verify licensing before you book.
Ask about HSA or FSA eligibility where applicable. Policies vary.
Considering underground or ceremonial settings
Underground and ceremonial options are part of today’s landscape. Laws vary by location, and safety practices differ widely. We do not broker, arrange, or endorse illegal activity. What we do provide is a clear and ethical path to decision making.
- Clarity, compare options side by side, including legal routes
- Safety, medication and history review to discuss with your clinician
- Vetting, facilitator criteria, ethics standards, scope of practice, and boundaries
- Preparation and integration, a plan so you are not doing this alone
Safety and screening
- Share all medications, especially SSRIs, MAOIs, stimulants, and blood-pressure drugs
- Review cardiac history, seizure risk, bipolar spectrum, psychosis risk, pregnancy, and sleep apnea
- Confirm monitoring, chaperone policies, and emergency planning
- If considering at-home or compounded ketamine, discuss supervision and current FDA alerts with your prescriber
What we do
- Education, safety screening guidance, and integration support
- Compare legal options and verify licensed programs
- Share the vetting questions we ask any facilitator (See our facilitator vetting checklist)
What we do not do
- Sell, supply, or store controlled substances
- Instruct on obtaining substances or connect to distributors
- Provide medical or legal advice
The Psychedelic Landscape in California (Cultural & Legal Overview)
What Oregon legalized
Oregon’s Measure 109 (ORS 475A) created a regulated system for licensed psilocybin services. Adults 21+ may participate without a prescription. Before any administration session at a licensed service center, clients complete a required preparation session with a licensed facilitator; consumption occurs on-site, followed by integration.
What it did not legalize
- It does not authorize at-home use, public possession, or unlicensed sales.
- It does not make psilocybin a prescription medicine.
- Local jurisdictions can restrict or opt out of licensed businesses; verify location availability.
Care today in Oregon
Most clients access care via: (1) licensed psilocybin services (prep → on-site administration → integration) at service centers; (2) medical ketamine or esketamine programs; or (3) underground or ceremonial settings, which carry legal risk and widely varying safety practices. We do not sell or supply substances, instruct on obtaining them, or broker illegal activity. Our role is to help you compare options, understand legal context, review safety with your clinicians, and plan thorough preparation and integration.
References: OHA: How access works · OPS program overview · SPRAVATO REMS · Colorado Natural Medicine
Oregon Psychedelic Therapy FAQs
Is psilocybin legal in Oregon?
Short answer: Yes—Oregon licenses psilocybin services statewide under Measure 109 (ORS 475A).
Adults 21+ can receive psilocybin services at a licensed service center with a licensed facilitator. A prescription or medical diagnosis is not required. Consumption happens on-site after a required preparation session; integration follows. How access works (OHA)
Do I need to live in Oregon?
Short answer: No—residency is not required for clients.
Clients from out of state may access services if they are 21+ with valid ID and complete the required preparation session; all dosing occurs on-site. OHA: Eligibility
Is this “therapy” in the medical sense?
Short answer: Oregon regulates psilocybin services, not medical treatment.
Facilitators are licensed under OPS regulations; the service is “supported adult use,” not a medical prescription. Many clients still coordinate with their healthcare providers for screening and follow-up, and we help you plan preparation and integration. OPS overview
What about local opt-outs?
Short answer: Some cities/counties have restricted or opted out of licensed businesses.
Availability can vary by locality. Verify the location of your chosen service center and any local rules before you book. (We’ll help you confirm.)
What are the medical options in Oregon?
Short answer: Ketamine (off-label for mental health) and esketamine in REMS-certified sites.
Esketamine (Spravato) is FDA-approved for TRD and must be administered in certified settings with monitoring. Ketamine for mental health is typically off-label and requires medical oversight. SPRAVATO REMS
Is MDMA-assisted therapy available?
Short answer: Not FDA-approved as of September 2025; access mainly via clinical trials.
If you’re exploring trials, we can help with preparation and integration planning around study requirements. FDA CRL made public
How much does it cost?
Short answer: Pricing varies by service center, session length, and facilitation level.
Licensed psilocybin services are paid to the service center and include required preparation and integration. Travel/lodging (if any) are additional. Medical ketamine/esketamine pricing depends on the clinic and insurance coverage.
Can your concierge help with safety and ethics?
Short answer: Yes—education, safety planning, and integration support; we do not broker illegal activity.
We’ll help you evaluate licensed options (and verify licensing), prepare questions for providers, review medications/contraindications with your clinicians, and build an integration plan. We do not sell or supply substances or instruct on obtaining them.
Next steps
Need help choosing? Our concierge can walk you through legal options in your area.

