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Legal / Policy / Geo-Legal

MDMA Therapy 2026 Update: Where Things Stand After the FDA Rejection

The FDA rejected Lykos Therapeutics’ application for MDMA-assisted therapy for PTSD in August 2024, and as of mid-2026 that decision stands. MDMA remains a Schedule I...

May 27, 2026 · 10 min
Executive

Psilocybin Grief Therapy: What High-Functioning People Often Carry

Psilocybin grief therapy is an emerging, clinically-studied approach for individuals whose grief has persisted well beyond the expected acute phase. For high-functioning professionals who have maintained...

May 20, 2026 · 9 min
Legal / Policy / Geo-Legal

Psychedelic Policy USA 2026: Mid-Year Federal and State Update

Psychedelic policy in the USA is moving faster in 2026 than at any point in recent history. A federal executive order, a wave of state-level bills,...

May 18, 2026 · 9 min
Conditions

Psychedelics and Sleep: What Research Suggests About Insomnia and Rest

Research into psilocybin sleep insomnia effects is still early, but the findings are genuinely interesting. Studies show psilocybin alters REM sleep and slow-wave activity in ways...

May 17, 2026 · 9 min
Preparation / Integration

Psilocybin Eating Disorder Treatment: Early Evidence and Cautions

Psilocybin eating disorder treatment is an emerging area of clinical research, with early trials in anorexia nervosa showing that the compound is well-tolerated and may help...

May 13, 2026 · 9 min
Substance Deep-Dives

Ketamine vs. Esketamine (Spravato): What the Difference Actually Means

Ketamine vs. esketamine (Spravato) is one of the most common points of confusion for people exploring treatment-resistant depression options. Both work through a similar mechanism in...

May 12, 2026 · 9 min
Science & Research

Psilocybin and the Aging Brain: What the Research Shows So Far

Research into psilocybin aging effects is accelerating, with preclinical studies pointing to neuroplasticity promotion, reduced neuroinflammation, and improvements in longevity biomarkers. The findings are genuinely interesting,...

May 10, 2026 · 9 min
Preparation / Integration

How to Talk to Your Doctor About Psychedelic Therapy

Talking to your doctor about psychedelic therapy is one of the most common points where people get stuck. This guide walks you through how to frame...

May 8, 2026 · 9 min
Science & Research

5-MeO-DMT Therapy: What the Research Shows and Why Risks Are Real

5-MeO-DMT therapy is attracting serious interest from researchers, executives, and people seeking relief from depression, anxiety, and trauma. The compound is potent, fast-acting, and increasingly the...

May 7, 2026 · 9 min
Conditions

Psilocybin OCD Treatment: What the Early Research Shows

Psilocybin OCD treatment is a small but growing area of clinical research, with early data suggesting meaningful symptom reductions for people who have not responded to...

May 5, 2026 · 8 min

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