
MDMA Therapy 2026 Update: Where Things Stand After the FDA Rejection
The FDA rejected Lykos Therapeutics’ application for MDMA-assisted therapy for PTSD in August 2024, and as of mid-2026 that decision stands. MDMA remains a Schedule I...

Psilocybin Grief Therapy: What High-Functioning People Often Carry
Psilocybin grief therapy is an emerging, clinically-studied approach for individuals whose grief has persisted well beyond the expected acute phase. For high-functioning professionals who have maintained...

Psychedelic Policy USA 2026: Mid-Year Federal and State Update
Psychedelic policy in the USA is moving faster in 2026 than at any point in recent history. A federal executive order, a wave of state-level bills,...

Psychedelics and Sleep: What Research Suggests About Insomnia and Rest
Research into psilocybin sleep insomnia effects is still early, but the findings are genuinely interesting. Studies show psilocybin alters REM sleep and slow-wave activity in ways...

Psilocybin Eating Disorder Treatment: Early Evidence and Cautions
Psilocybin eating disorder treatment is an emerging area of clinical research, with early trials in anorexia nervosa showing that the compound is well-tolerated and may help...

Ketamine vs. Esketamine (Spravato): What the Difference Actually Means
Ketamine vs. esketamine (Spravato) is one of the most common points of confusion for people exploring treatment-resistant depression options. Both work through a similar mechanism in...

Psilocybin and the Aging Brain: What the Research Shows So Far
Research into psilocybin aging effects is accelerating, with preclinical studies pointing to neuroplasticity promotion, reduced neuroinflammation, and improvements in longevity biomarkers. The findings are genuinely interesting,...

How to Talk to Your Doctor About Psychedelic Therapy
Talking to your doctor about psychedelic therapy is one of the most common points where people get stuck. This guide walks you through how to frame...

5-MeO-DMT Therapy: What the Research Shows and Why Risks Are Real
5-MeO-DMT therapy is attracting serious interest from researchers, executives, and people seeking relief from depression, anxiety, and trauma. The compound is potent, fast-acting, and increasingly the...

Psilocybin OCD Treatment: What the Early Research Shows
Psilocybin OCD treatment is a small but growing area of clinical research, with early data suggesting meaningful symptom reductions for people who have not responded to...
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