Psilocybin Insomnia Treatment: Can It Reset Your Sleep?
There is no strong evidence that psilocybin insomnia treatment works as a direct cure for a sleep disorder. What research shows is that sleep quality often...
Psilocybin PTSD Treatment: Where the Research Stands in 2026
Psilocybin PTSD treatment is still investigational. The strongest evidence so far is a single small open-label trial of 22 people, which showed meaningful symptom reductions but...
Psilocybin Smoking Cessation: What the Research Shows
Psilocybin smoking cessation research from Johns Hopkins has produced abstinence rates well above those seen with nicotine patches or standard medications, with a 2014 pilot showing...
Microdosing for Depression and Anxiety: What the Clinical Evidence Actually Shows
Placebo-controlled trials of microdosing have consistently failed to show that low doses of psilocybin or LSD outperform placebo for mood, anxiety, or well-being. People taking a...
Psilocybin for Alcohol Use Disorder: The Johns Hopkins Breakthrough Study
In the largest controlled trial to date, psilocybin for alcohol use disorder cut heavy drinking days from 23.6 percent to 9.7 percent over eight months when...
Psilocybin for Treatment-Resistant Depression: What the Clinical Trials Actually Show
In controlled clinical trials, psilocybin for treatment-resistant depression has produced rapid and often durable symptom reductions after one or two guided sessions, with the largest study...
Psychedelics and Trauma: How These Medicines Work at the Neurological Level
Psychedelics appear to address trauma by temporarily increasing the brain’s capacity to change, opening a window in which fear-based memories become editable rather than fixed. The...
The Best Psychedelic for Addiction? Comparing Ibogaine, Psilocybin, Ketamine, Ayahuasca
There is no single best psychedelic for addiction, because the evidence is organized by which substance you are trying to stop. Psilocybin has the strongest controlled-trial...
The Best Psychedelic for PTSD? Comparing MDMA, Psilocybin, and Ketamine
MDMA-assisted therapy has the strongest evidence of any psychedelic for PTSD, with two completed Phase 3 trials showing that a majority of participants no longer met...
Alcoholism Psychedelic Therapy: From Bill Wilson to Clinical Trials
Modern trials suggest that psilocybin combined with structured psychotherapy can meaningfully reduce heavy drinking in people with alcohol use disorder, with the strongest evidence coming from...
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