The Best Psychedelic for Depression? Psilocybin vs Ketamine vs LSD vs Ayahuasca
There is no single best psychedelic for depression, but the evidence is not evenly distributed. Ketamine has the strongest legal access and the fastest onset, psilocybin...
5-MeO-DMT for Depression and Anxiety: What the Evidence Shows
Research on 5-MeO-DMT for depression and anxiety, particularly in the context of 5-MeO-DMT depression anxiety treatment, is genuinely early, but it is no longer purely anecdotal....
Addiction Psychedelic Therapy: What the Science Says About Breaking the Cycle
Early clinical research on addiction and psychedelic therapy is genuinely promising, with controlled trials showing meaningful reductions in heavy drinking and high abstinence rates in tobacco...
Ibogaine for Opioid Addiction: What the Evidence and the Risks Actually Show
Ibogaine opioid addiction treatment can interrupt physical withdrawal and reduce cravings after a single session, an effect no approved medication produces. The evidence comes almost entirely...
Ayahuasca Addiction Treatment: What the Evidence Shows
Research on ayahuasca addiction treatment is both encouraging and genuinely limited. Observational studies and large international surveys report reduced alcohol, tobacco, and cocaine use following ceremonial...
Sexual Trauma and Psychedelic Therapy: What the Research Shows about Healing and Trust
For people healing from sexual trauma, psychedelic therapy is being studied as a way to work with the fear, shame, and broken trust that conventional treatments...
Ayahuasca Depression Treatment: What the First Randomized Trial Showed
In 2019, Brazilian researchers published the first randomized placebo-controlled trial of a psychedelic in treatment-resistant depression, and it tested ayahuasca. Seven days after a single dose,...
Ibogaine Therapy: A Complete Guide to the Most Powerful and Risky Psychedelic
Ibogaine is a plant-derived psychedelic with real promise for interrupting opioid addiction and, more recently, for treating trauma, but it carries a risk of fatal heart...
LSD Alcoholism Treatment: The Forgotten Research That Started Psychedelic Therapy
Six randomized controlled trials of LSD alcoholism treatment conducted between the 1950s and 1970s, pooled in a 2012 meta-analysis of 536 participants, found that a single...
5-MeO-DMT: A Complete Guide to One of the Most Intense Psychedelics
5-MeO-DMT is a fast-acting psychedelic found in the secretion of the Sonoran Desert toad and also made synthetically, known for producing near-total loss of ordinary awareness...
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