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Substance Deep-Dives

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The Best Psychedelic for Addiction? Comparing Ibogaine, Psilocybin, Ketamine, Ayahuasca

There is no single best psychedelic for addiction, because the evidence is organized by which substance you are trying to stop. Psilocybin has the strongest controlled-trial...

August 11, 2026 · 10 min
Conditions

Insomnia Psychedelic Therapy: What Emerging Research Shows

Insomnia psychedelic therapy is an early research area with promising but limited evidence. Studies show sleep quality often improves after psilocybin, though usually as a downstream...

August 11, 2026 · 8 min
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The Best Psychedelic for PTSD? Comparing MDMA, Psilocybin, and Ketamine

MDMA-assisted therapy has the strongest evidence of any psychedelic for PTSD, with two completed Phase 3 trials showing that a majority of participants no longer met...

August 10, 2026 · 10 min
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Alcoholism Psychedelic Therapy: From Bill Wilson to Clinical Trials

Modern trials suggest that psilocybin combined with structured psychotherapy can meaningfully reduce heavy drinking in people with alcohol use disorder, with the strongest evidence coming from...

August 10, 2026 · 8 min
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The Best Psychedelic for Depression? Psilocybin vs Ketamine vs LSD vs Ayahuasca

There is no single best psychedelic for depression, but the evidence is not evenly distributed. Ketamine has the strongest legal access and the fastest onset, psilocybin...

August 9, 2026 · 10 min
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5-MeO-DMT for Depression and Anxiety: What the Evidence Shows

Research on 5-MeO-DMT for depression and anxiety, particularly in the context of 5-MeO-DMT depression anxiety treatment, is genuinely early, but it is no longer purely anecdotal....

August 9, 2026 · 9 min
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Addiction Psychedelic Therapy: What the Science Says About Breaking the Cycle

Early clinical research on addiction and psychedelic therapy is genuinely promising, with controlled trials showing meaningful reductions in heavy drinking and high abstinence rates in tobacco...

August 9, 2026 · 8 min
Conditions

Ibogaine for Opioid Addiction: What the Evidence and the Risks Actually Show

Ibogaine opioid addiction treatment can interrupt physical withdrawal and reduce cravings after a single session, an effect no approved medication produces. The evidence comes almost entirely...

August 8, 2026 · 10 min
Substance Deep-Dives

San Pedro and Mescaline: A Complete Guide to Cactus Medicine

San Pedro is a mescaline-containing cactus native to the Andes, where it has been used ceremonially for thousands of years under the name Huachuma. Mescaline, its...

August 8, 2026 · 10 min
Science & Research

Ayahuasca Addiction Treatment: What the Evidence Shows

Research on ayahuasca addiction treatment is both encouraging and genuinely limited. Observational studies and large international surveys report reduced alcohol, tobacco, and cocaine use following ceremonial...

August 7, 2026 · 10 min

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