Ayahuasca Addiction Treatment: What the Evidence Shows
Research on ayahuasca addiction treatment is both encouraging and genuinely limited. Observational studies and large international surveys report reduced alcohol, tobacco, and cocaine use following ceremonial...
Sexual Trauma and Psychedelic Therapy: What the Research Shows about Healing and Trust
For people healing from sexual trauma, psychedelic therapy is being studied as a way to work with the fear, shame, and broken trust that conventional treatments...
Ayahuasca Depression Treatment: What the First Randomized Trial Showed
In 2019, Brazilian researchers published the first randomized placebo-controlled trial of a psychedelic in treatment-resistant depression, and it tested ayahuasca. Seven days after a single dose,...
Childhood Trauma and Psychedelic Therapy: Healing Developmental Wounds in Adulthood
Childhood trauma is not a formal diagnosis, yet early and repeated adversity reshapes the developing brain and often surfaces decades later as depression, anxiety, or PTSD....
Ibogaine Therapy: A Complete Guide to the Most Powerful and Risky Psychedelic
Ibogaine is a plant-derived psychedelic with real promise for interrupting opioid addiction and, more recently, for treating trauma, but it carries a risk of fatal heart...
LSD Alcoholism Treatment: The Forgotten Research That Started Psychedelic Therapy
Six randomized controlled trials of LSD alcoholism treatment conducted between the 1950s and 1970s, pooled in a 2012 meta-analysis of 536 participants, found that a single...
LSD Depression Treatment: The Renewed Clinical Interest in Lysergic Acid
LSD depression treatment has moved from a decades-long research freeze into late-stage clinical trials, with a Phase 3 study of a pharmaceutical LSD formulation reporting positive...
5-MeO-DMT: A Complete Guide to One of the Most Intense Psychedelics
5-MeO-DMT is a fast-acting psychedelic found in the secretion of the Sonoran Desert toad and also made synthetically, known for producing near-total loss of ordinary awareness...
LSD Anxiety Treatment: What Modern Clinical Trials Are Finding
Research on LSD anxiety treatment has produced some of the strongest controlled data in psychedelic medicine. A 2025 Phase 2b trial published in JAMA found that...
Complex PTSD Psychedelic Therapy: Why cPTSD Is Different from PTSD
Complex PTSD (cPTSD) differs from PTSD because it develops from prolonged, repeated trauma, and it adds lasting disturbances in emotional regulation, self-worth, and relationships on top...
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