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Mental Health

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Science & Research

Psilocybin PTSD Therapy: What the 2026 Clinical Evidence Shows

Psilocybin PTSD therapy is no longer a fringe concept. A growing body of clinical research, including Phase 2 trials published in 2025, shows that a single...

April 20, 2026 · 10 min
Conditions

The default mode network, explained: why psychedelics reset how your brain thinks

The default mode network is a cluster of brain regions responsible for self-referential thinking, rumination, and your ongoing sense of “I.” Research on default mode network...

April 16, 2026 · 9 min
Therapy

Psychedelics for Depression: What the 2026 Research Actually Shows

Quick Answer  Psilocybin and other psychedelics show real, measurable promise for depression, particularly treatment-resistant cases. But the evidence in 2026 is more complicated, more honest, and...

March 22, 2026 · 8 min
Therapy

LSD for Anxiety: What a Landmark Clinical Trial Actually Found

Quick answer: A LSD For Anxiety randomized, placebo-controlled Phase 2b trial published in JAMA found that a single oral dose of MM120, an investigational LSD formulation...

November 30, 2025 · 7 min
Legal / Policy / Geo-Legal

MDMA Therapy FDA Decision, What the Rejection Letter Means for Seekers

The FDA rejected Lykos Therapeutics’ application for MDMA-assisted therapy for PTSD, citing three specific concerns: gaps in safety reporting, insufficient evidence that benefits lasted over time,...

November 22, 2025 · 8 min
Guides

Ketamine Therapy Preparation: What to Expect and Why It Matters

Ketamine therapy preparation is not a formality you complete before the real thing begins. It is a functional part of what makes the treatment work. What...

August 12, 2025 · 10 min
Therapy

Healing Together: Psychedelic Therapy, Partnership, and the Power of Personalized Guidance

Psychedelic guide matching is one of the most important decisions a seeker can make, and at JourneyOM, it is never left to an algorithm. This post...

July 17, 2025 · 7 min
Legal / Policy / Geo-Legal

RFK Jr. and Psychedelic Therapy: What Seekers Should Know

RFK Jr. psychedelic therapy support has brought real political attention to substances like psilocybin, MDMA, and ibogaine. For seekers already exploring this space, the shift matters....

July 16, 2025 · 8 min
Therapy

Psychedelic Nasal Spray for Depression: What the Research Shows

A psychedelic nasal spray for depression called BPL-003 has produced rapid, meaningful antidepressant effects in clinical trials, earning FDA Breakthrough Therapy designation in late 2025. The...

July 7, 2025 · 7 min
Therapy

Psychedelic Therapy for Veterans: What the Research Shows

Psychedelic therapy for veterans is one of the most actively researched areas in mental health today. Clinical trials involving MDMA and psilocybin have shown meaningful reductions...

July 5, 2025 · 10 min

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