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Substance Deep-Dives

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Conditions

The default mode network, explained: why psychedelics reset how your brain thinks

The default mode network is a cluster of brain regions responsible for self-referential thinking, rumination, and your ongoing sense of “I.” Research on default mode network...

April 16, 2026 · 9 min →
Science & Research

What executives are actually using psychedelic therapy for (and what the data shows)

Psychedelic therapy for executives is moving beyond reputation and into clinical evidence. A growing number of C-suite leaders are using professionally supported psilocybin and ketamine experiences...

April 15, 2026 · 8 min →
Therapy

Psychedelics for Depression: What the 2026 Research Actually Shows

Quick Answer  Psilocybin and other psychedelics show real, measurable promise for depression, particularly treatment-resistant cases. But the evidence in 2026 is more complicated, more honest, and...

March 22, 2026 · 8 min →
Psilocybin

Microdosing Psychedelics — Promise, Risks, and Where We Go from Here

Quick answer: Microdosing psychedelics means taking very small, sub-perceptual doses of substances such as psilocybin or LSD, usually on a repeated schedule rather than in a...

March 21, 2026 · 5 min →
Legal / Policy / Geo-Legal

MDMA Therapy FDA Decision, What the Rejection Letter Means for Seekers

The FDA rejected Lykos Therapeutics’ application for MDMA-assisted therapy for PTSD, citing three specific concerns: gaps in safety reporting, insufficient evidence that benefits lasted over time,...

November 22, 2025 · 8 min →
Guides

It’s Supposed To Hurt… | JourneyŌM Guides Series

Brian, a JourneyŌM guide reflects on presence, capacity, and the steady work of being human. It’s Supposed To Hurt… …at least some of the time. I’ve...

August 20, 2025 · 7 min →
Therapy

Ketamine Therapy Preparation: What to Expect and Why It Matters

Ketamine therapy preparation is not a formality you complete before the real thing begins. It is a functional part of what makes the treatment work. What...

August 12, 2025 · 10 min →
Therapy

Healing Together: Psychedelic Therapy, Partnership, and the Power of Personalized Guidance

Psychedelic guide matching is one of the most important decisions a seeker can make, and at JourneyŌM, it is never left to an algorithm. This post...

July 17, 2025 · 8 min →
Legal / Policy / Geo-Legal

RFK Jr. and Psychedelic Therapy: What Seekers Should Know

RFK Jr. psychedelic therapy support has brought real political attention to substances like psilocybin, MDMA, and ibogaine. For seekers already exploring this space, the shift matters....

July 16, 2025 · 8 min →
Therapy

Psychedelic Therapy for Veterans: What the Research Shows

Psychedelic therapy for veterans is one of the most actively researched areas in mental health today. Clinical trials involving MDMA and psilocybin have shown meaningful reductions...

July 5, 2025 · 10 min →

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