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Substance Deep-Dives

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Executive

MDMA Couples Therapy: When Shared Healing Requires Shared Vulnerability

MDMA couples therapy has been tested in only one published trial: a 2020 uncontrolled pilot of six couples that combined MDMA with Cognitive-Behavioural Conjoint Therapy for...

August 3, 2026 · 9 min
Conditions

MDMA for Childhood Trauma: What the Research Shows About Healing Early Wounds

No clinical trial has yet tested MDMA-assisted therapy specifically for childhood trauma as a standalone diagnosis, so the real answer is that direct evidence does not...

August 2, 2026 · 10 min
Science & Research

LSD Therapy Guide: From Hofmann’s Discovery to Modern Clinical Use

LSD-assisted therapy uses a single high dose of lysergic acid diethylamide, given alongside structured psychological support, to treat anxiety and related conditions. Modern controlled trials, including...

August 2, 2026 · 10 min
Preparation / Integration

MDMA for Sexual Trauma: How the Therapeutic Model Addresses Trust and Safety

MDMA-assisted therapy has strong Phase 3 evidence for PTSD generally, and sexual trauma survivors were well represented in those trials, but no published randomized trial has...

August 1, 2026 · 10 min
Conditions

PTSD Psychedelic Therapy: A Science-Based Overview

Among psychedelic approaches to PTSD, MDMA-assisted therapy has the strongest evidence, with two Phase 3 trials showing large symptom reductions, though the FDA declined to approve...

August 1, 2026 · 8 min
Conditions

MDMA for Complex PTSD: Why Standard Treatments Fall Short

MDMA for complex PTSD has not been tested in a dedicated clinical trial, so no treatment can honestly claim proven results for this diagnosis. What we...

July 31, 2026 · 10 min
Conditions

MDMA PTSD Therapy: Inside the Most Promising Psychedelic Research Ever Conducted

MDMA PTSD therapy produced the strongest results of any psychedelic research program to date. Across two Phase 3 trials, roughly seven in ten participants no longer...

July 31, 2026 · 9 min
Conditions

Psychedelic Therapy for Anxiety Disorders: What the Research Shows

The strongest evidence for psychedelic therapy in anxiety disorders comes from trials treating anxiety tied to a life-threatening illness, where single doses of psilocybin or LSD...

July 31, 2026 · 9 min
Legal / Policy / Geo-Legal

At Home Ketamine Therapy vs. In-Clinic: Safety, Efficacy, and What to Know

At home ketamine therapy uses sublingual lozenges prescribed and monitored remotely, while in-clinic care typically uses intravenous or intramuscular ketamine with a clinician physically present. Observational...

July 30, 2026 · 10 min
Substance Deep-Dives

MDMA-Assisted Therapy: A Complete Guide to the Science, Experience, and Access

MDMA-assisted therapy pairs a carefully dosed session of MDMA with structured psychotherapy, and in two Phase 3 trials it produced large reductions in PTSD symptoms, with...

July 30, 2026 · 9 min

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